Although serological correlates for protection have not been established for the pneumococcal serotypes, a threshold level of ≥0.3 mcg/mL was evaluated. Generic Name: diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed Store refrigerated between 2° and 8°C (36° and 46°F). Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Indications: Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. For active immunization against diphtheria, tetanus, and pertussis as a 5-dose series in infants and children aged 6 weeks through 6 years (prior to the 7th birthday). The first dose may be given as early as 6 weeks of age. Do not freeze. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Epinephrine and other appropriate agents used for the control of immediate allergic reactions must be immediately available should an acute anaphylactic reaction occur. Vaccines work by ‘teaching’ the immune system (the body’s natural defences) to defend the body against the infections. Pertussis (whooping cough) is a disease of the respiratory tract caused by B. pertussis. Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed, azithromycin, Zithromax, clarithromycin, Daptacel (DTaP), tetanus immune globulin, Adacel (Tdap), Boostrix (Tdap), Quadracel, diphtheria toxoid / tetanus toxoid. One month after the third dose of Infanrix, the response rates to each pertussis antigen were similar in all 3 studies. A serum diphtheria antitoxin level of 0.01 IU/mL is the lowest level giving some degree of protection; a level of 0.1 IU/mL is regarded as protective.1, Tetanus is an acute toxin-mediated infectious disease caused by a potent exotoxin released by C. tetani. Infanrix is formulated without preservatives. In the fifth-dose study, a large swelling reaction was defined as swelling that involved >50% of the injected upper arm length and that was associated with a >30 mm increase in mid-upper arm circumference within 4 days following vaccination. a with Separate Concomitant Administration of Infanrix, ENGERIX-B, IPV, Haemophilus b (Hib) Conjugate Vaccine, and Pneumococcal Conjugate Vaccine (PCV7) (Modified Intent-to-Treat Cohort), a with Infanrix Administered as the Fourth Dose following 3 Previous Doses of Infanrix or PEDIARIX (Total Vaccinated Cohort), a with a Fifth Consecutive Dose of Infanrix when Coadministered with IPV and MMR Vaccine (Total Vaccinated Cohort), Corynebacterium diphtheriae (C. diphtheriae), diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed suspension, We comply with the HONcode standard for trustworthy health information -, diphtheria and tetanus toxoids and acellular pertussis vaccine adsorbed. Less Common and Serious General Adverse Reactions. The corresponding efficacy of Infanrix against ≥14 days of any cough or paroxysmal cough were 73% (95% CI: 59, 82) and 84% (95% CI: 71, 91), respectively. IPV manufactured by Sanofi Pasteur SA. Levels of tetanus antitoxin ≥0.01 IU/mL were achieved in 100% of the sera tested. The protective efficacy of Infanrix was calculated to be 89% (95% CI: 77, 95), with no indication of waning of protection up until the time of the booster vaccination. ©2019 GSK group of companies or its licensor. When a child is given the vaccine, the immune system recognises the parts of the bacteria and viruses in the vaccine as ‘foreign’ and makes antibodies against them. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. Vaccine efficacy after 3 doses and with no booster dose in the second year of life was assessed in 2 subsequent follow-up periods. Index cases were identified by spontaneous presentation to a physician. Levels of diphtheria antitoxin ≥0.01 IU/mL were achieved in 100% of the sera tested. Infanrix is indicated for active immunization against diphtheria, tetanus, and pertussis as a 5-dose series in infants and children aged 6 weeks through 6 years (prior to the 7th birthday). Overall, between 95 and 100% of the children had antibodies to diphtheria, tetanus, pertussis, hepatitis B virus, polioviruses, and Hib, 1 month after the vaccination course. Subsequent injections should be given in different areas. Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Infanrix hexa have been included in the summary of product characteristics and the package leaflet. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. The diphtheria toxin is produced by growing Corynebacterium diphtheriae (C. diphtheriae) in Fenton medium containing a bovine extract. Discard if the vaccine has been frozen. The incidence of rectal temperature ≥104°F, hypotonic-hyporesponsive episodes, and persistent crying ≥3 hours following administration of Infanrix was significantly less than that following administration of whole-cell DTP vaccine. Because the pertussis antigen components of Infanrix and PEDIARIX [Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine] are the same, Infanrix may be used to complete a DTaP vaccination series initiated with PEDIARIX. Adverse reactions (rates per 1,000 doses) occurring within 7 days following any of the first 3 doses included: unusual crying (0.09), febrile seizure (0.0), afebrile seizure (0.13), and hypotonic-hyporesponsive episodes (0.01). Sufficient data are not available on the safety and effectiveness of interchanging Infanrix and Diphtheria and Tetanus Toxoids and Acellular Pertussis (DTaP) vaccines from different manufacturers for successive doses of the DTaP vaccination series. A VERO cell toxin-neutralizing test confirmed the ability of infant sera (N = 45), obtained one month after a 3-dose primary series, to neutralize diphtheria toxin. A double-blind, randomized, active Diphtheria and Tetanus Toxoids (DT)-controlled trial conducted in Italy assessed the absolute protective efficacy of Infanrix when administered at 2, 4, and 6 months of age. This helps to protect against the diseases that these bacteria and viruses cause. Whooping Cough Each 0.5-mL dose contains aluminum hydroxide as adjuvant (not more than 0.625 mg aluminum by assay) and 4.5 mg of sodium chloride. Over 3,000 of the children received a course of vaccination with Infanrix hexa. Before sharing sensitive information, make sure you're on a federal government site. Shake vigorously to obtain a homogeneous, turbid, white suspension. Adverse events in the remainder of the cohort were reported via report cards which were returned by mail approximately 28 days after the third dose of vaccine. If Guillain-Barré syndrome occurs within 6 weeks of receipt of a prior vaccine containing tetanus toxoid, the decision to give any tetanus toxoid-containing vaccine, including Infanrix, should be based on careful consideration of the potential benefits and possible risks. Diphtheria is an acute toxin-mediated infectious disease caused by toxigenic strains of C. diphtheriae. Available for Android and iOS devices. Increase in mid-thigh circumference, >40 mm. For more information, see the package leaflet. Alternatively, such individuals may be referred to an allergist for evaluation if immunization with any of these components is being considered. Total Vaccinated Cohort = All subjects who received a dose of study vaccine. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Hib conjugate vaccine and PCV7 manufactured by Wyeth Pharmaceuticals Inc. IPV manufactured by Sanofi Pasteur SA. A prospective efficacy trial was also conducted in Germany employing a household contact study design. Calculation of vaccine efficacy was based on attack rates of pertussis in household contacts classified by vaccination status. Protection against disease is due to the development of neutralizing antibodies to the tetanus toxin. In a U.S. study, the safety of a fifth consecutive dose of Infanrix coadministered at separate sites with a fourth dose of IPV (Sanofi Pasteur SA) and a second dose of MMR vaccine (Merck & Co., Inc.) was evaluated in 1,053 children aged 4 to 6 years. Prior to administration, the healthcare provider should review the patient’s immunization history for possible vaccine hypersensitivity. For more information about treatment with Infanrix hexa, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist. Protection against disease is due to the development of neutralizing antibodies to the diphtheria toxin. One month after the third dose of Hib conjugate vaccine, 90% of 72 infants had anti-PRP (polyribosyl-ribitol-phosphate) ≥1.0 mcg/mL. Manufactured by GlaxoSmithKline Biologicals. Cards from the whole cohort were returned at subsequent visits and were supplemented by spontaneous reporting by parents and a medical history after the first and second doses of vaccine. Hepatitis B When a decision is made to withhold tetanus toxoid, other available vaccines should be given, as indicated. A 0.5-mL dose of Infanrix is approved for intramuscular administration in infants and children aged 6 weeks through 6 years (prior to the 7th birthday) as a 5-dose series. Infanrix hexa is given by deep injection into a muscle. In clinical trials, Infanrix was given concomitantly with Hib conjugate vaccine, pneumococcal 7-valent conjugate vaccine, hepatitis B vaccine, IPV, and the second dose of MMR vaccine [see Adverse Reactions (6.1), Clinical Studies (14.3)]. It promotes the immune system to act against microorganisms to prevent such infections. The incidence of large swelling reactions following the fifth consecutive dose of Infanrix was 1.0%. Among subjects, 85% were white, 6% were Hispanic, 6% were black, 1% were Asian, and 2% were of other racial/ethnic groups. STN: BL 103647Proper Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine AdsorbedTradename: INFANRIXManufacturer: GlaxoSmithKline BiologicalsIndications: An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, November 6, 2019 Approval Letter - INFANRIX, Supporting Documents older than three years - INFANRIX. Syncope (fainting) can occur in association with administration of injectable vaccines, including Infanrix. This means that the active substances are fixed onto aluminium compounds, to stimulate a better response. PT and FHA are isolated from the fermentation broth; pertactin is extracted from the cells by heat treatment and flocculation. Immune responses were measured in sera obtained approximately 1 month after the third dose of vaccines. Both toxins are detoxified with formaldehyde, concentrated by ultrafiltration, and purified by precipitation, dialysis, and sterile filtration. The tip caps of the prefilled syringes contain natural rubber latex; the plungers are not made with natural rubber latex. When the definition of pertussis was expanded to include clinically milder disease, with infection confirmed by culture and/or serologic testing, the efficacy of Infanrix against ≥7 days of any cough was 67% (95% CI: 52, 78) and against ≥7 days of paroxysmal cough was 81% (95% CI: 68, 89). All vaccines were administered at 2, 4, and 6 months of age. FHA and pertactin are treated with formaldehyde. In the U.S. booster immunization studies in which Infanrix was administered as the fourth or fifth dose in the DTaP series following previous doses with Infanrix or PEDIARIX, large swelling reactions of the limb injected with Infanrix were assessed. The European Commission granted a marketing authorisation valid throughout the EU for Infanrix hexa on 23 October 2000. Because of the uncertainty as to which component of the vaccine might be responsible, no further vaccination with any of these components should be given. Pertussis vaccine should not be administered to individuals with these conditions until a treatment regimen has been established and the condition has stabilized. Of the 173 household contacts who had not received a pertussis vaccine, 96 developed WHO-defined pertussis, as compared with 7 of 112 contacts vaccinated with Infanrix. Infanrix Hexa Vaccine is a combination of multiple vaccines. Manufacturer: GlaxoSmithKline Biologicals. The potency of the acellular pertussis components (PT, FHA, and pertactin) is determined by enzyme-linked immunosorbent assay (ELISA) on sera from previously immunized mice. The overall incidence of large swelling reactions occurring within 4 days (Day 0-Day 3) following Infanrix was 2.3%. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to vaccination. Poliomyelitis Household contacts of index cases were monitored for incidence of pertussis by a physician who was blinded to the vaccination status of the household. The tip caps of the prefilled syringes contain natural rubber latex which may cause allergic reactions. The choice of booster vaccine depends on official recommendations. In a German safety study that enrolled 22,505 infants (66,867 doses of Infanrix administered as a 3-dose primary series at 3, 4, and 5 months of age), all subjects were monitored for unsolicited adverse events that occurred within 28 days following vaccination using report cards. Infants who did not participate in the safety and immunogenicity study could have received a DTwP vaccine or DT vaccine. Infanrix should not be mixed with any other vaccine in the same syringe or vial. Households with at least one other member (i.e., besides index case) aged 6 through 47 months were enrolled. There is no well-established serological correlate of protection for pertussis. Changing needles between drawing vaccine from a vial and injecting it into a recipient is not necessary unless the needle has been damaged or contaminated. The series consists of a primary immunization course of 3 doses administered at 2, 4, and 6 months of age (at intervals of 4 to 8 weeks), followed by 2 booster doses, administered at 15 to 20 months of age and at 4 to 6 years of age. For the prefilled syringes, attach a sterile needle and administer intramuscularly. Diphtheria and tetanus toxoids and pertussis antigens (PT, FHA, and pertactin) are individually adsorbed onto aluminum hydroxide. Among 121 subjects who had not received a birth dose of hepatitis B vaccine, 99.2% had anti-HBsAg (hepatitis B surface antigen) ≥10 mIU/mL following the third dose of ENGERIX-B. After 3 doses, the absolute protective efficacy of Infanrix against WHO-defined typical pertussis (21 days or more of paroxysmal cough with infection confirmed by culture and/or serologic testing) was 84% (95% CI: 76, 89). The vaccine can only be obtained with a prescription. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a vaccine cannot be directly compared with rates in the clinical trials of another vaccine and may not reflect the rates observed in practice. Infanrix is not approved for use in these age groups. Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune response to Infanrix. Vaccines work by ‘teaching’ the immune system (the body’s natural defences) to defend the body against the infections. Tetanus toxin is produced by growing Clostridium tetani (C. tetani) in a modified Latham medium derived from bovine casein. Available for Android and iOS devices. Encephalopathy, headache, hypotonia, syncope. DTaP vs Tdap Vaccines - What's the difference between them? MMR vaccine manufactured by Merck & Co., Inc. CLOSTRIDIUM TETANI TOXOID ANTIGEN (FORMALDEHYDE INACTIVATED), CORYNEBACTERIUM DIPHTHERIAE TOXOID ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS TOXOID ANTIGEN (FORMALDEHYDE, GLUTARALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS FILAMENTOUS HEMAGGLUTININ ANTIGEN (FORMALDEHYDE INACTIVATED), BORDETELLA PERTUSSIS PERTACTIN ANTIGEN (FORMALDEHYDE INACTIVATED). Infanrix (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) is a noninfectious, sterile vaccine for intramuscular administration. Last updated on Nov 1, 2019. In a U.S. study, Infanrix was given concomitantly, at separate sites, with Hib conjugate vaccine (Sanofi Pasteur SA) at 2, 4, and 6 months of age. In a subset of subjects (n = 2,457), these cards were standardized diaries which solicited specific adverse reactions that occurred within 8 days of each vaccination in addition to unsolicited adverse events which occurred from enrollment until approximately 30 days following the third vaccination. Infanrix hexa contains the following active substances: Infanrix hexa is available as a powder and suspension that are made up into a suspension for injection. Syncope can be accompanied by transient neurological signs such as visual disturbance, paresthesia, and tonic-clonic limb movements. Apnea following intramuscular vaccination has been observed in some infants born prematurely. PT is detoxified using glutaraldehyde and formaldehyde. Infanrix is a suspension for injection available in 0.5-mL single-dose vials and 0.5-mL single-dose, prefilled TIP‑LOK syringes. Do not use if resuspension does not occur with vigorous shaking. The population used in the primary analysis of the efficacy of Infanrix included 4,481 infants vaccinated with Infanrix and 1,470 DT vaccinees. In these studies, 29,243 infants have received Infanrix in primary series studies: 6,081 children have received a fourth consecutive dose of Infanrix, 1,764 children have received a fifth consecutive dose of Infanrix, and 559 children have received a dose of Infanrix following 3 doses of PEDIARIX. Select one or more newsletters to continue. The most common side effects with Infanrix hexa (seen in more than 1 in 10 doses of the vaccine) are swelling, pain and redness at the injection site, loss of appetite, fever of 38ºC or more, tiredness, abnormal crying, irritability and restlessness. The vial stoppers are not made with natural rubber latex. Approximately 95,000 doses of Infanrix have been administered in clinical studies. A follow-up period from 24 months to a mean age of 33 months was conducted in a partially unblinded cohort (children who received DT were offered pertussis vaccine and those who declined were retained in the study cohort). Severe allergic reaction (e.g., anaphylaxis) after a previous dose of any diphtheria toxoid-, tetanus toxoid-, or pertussis-containing vaccine, or to any component of Infanrix is a contraindication [see Description (11)]. Proper Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed. When the definition of pertussis was expanded to include clinically milder disease with respect to type and duration of cough, with infection confirmed by culture and/or serologic testing, the efficacy of Infanrix was calculated to be 71% (95% CI: 60, 78) against >7 days of any cough and 73% (95% CI: 63, 80) against ≥14 days of any cough. For the vials, use a sterile needle and sterile syringe to withdraw the 0.5-mL dose and administer intramuscularly. ATC Code: J07CA09Marketing Authorisation Holder: GlaxoSmithKline Biologicals S.A.Active Substance: diphtheria toxoid / tetanus toxoid / Bordetella pertussis antigens (pertussis toxoid, filamentous haemagglutinin, pertactin) / hepatitis B surface antigen / poliovirus (inactivated) (type-1 (Mahoney strain), type-2 (MEF-1 strain), type-3 (Saukett strain)) / Haemophilus influenzae type-b polysaccharide Respiratory, Thoracic, and Mediastinal Disorders. The average age of infants vaccinated with Infanrix at the end of follow-up in this trial was 13 months (range: 6 to 25 months). The European Medicines Agency therefore decided that Infanrix hexa’s benefits are greater than its risks and recommended that it be given marketing authorisation. The safety of Infanrix hexa is similar to other vaccines used to prevent these conditions. The .gov means it’s official.Federal government websites often end in .gov or .mil. Infanrix has not been evaluated for carcinogenic or mutagenic potential or for impairment of fertility. Infanrix is available in 0.5-mL single-dose vials and 0.5-mL single-dose, disposable, prefilled TIP‑LOK syringes (packaged without needles): NDC 58160-810-01 Vial in Package of 10: NDC 58160-810-11, NDC 58160-810-43 Syringe in Package of 10: NDC 58160-810-52. Provide the following information to the parent or guardian: ENGERIX-B, Infanrix, PEDIARIX, and TIP-LOK are trademarks owned by or licensed to the GSK group of companies. Encephalopathy (e.g., coma, decreased level of consciousness, prolonged seizures) within 7 days of administration of a previous dose of a pertussis-containing vaccine that is not attributable to another identifiable cause is a contraindication to administration of any pertussis-containing vaccine, including Infanrix. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. In a U.S. study, Infanrix was given concomitantly, at separate sites, with ENGERIX-B, IPV (Sanofi Pasteur SA), pneumococcal 7-valent conjugate (PCV7), and Hib conjugate vaccines (Wyeth Pharmaceuticals Inc.) at 2, 4, and 6 months of age. The preferred administration site is the anterolateral aspect of the thigh for most infants aged younger than 12 months and the deltoid muscle of the upper arm for most children aged 12 months through 6 years. Each 0.5-mL dose is formulated to contain 25 Lf of diphtheria toxoid, 10 Lf of tetanus toxoid, 25 mcg of inactivated pertussis toxin (PT), 25 mcg of filamentous hemagglutinin (FHA), and 8 mcg of pertactin (69 kiloDalton outer membrane protein). If any of the following reactions occur in temporal relation to receipt of a pertussis-containing vaccine, the decision to give any pertussis-containing vaccine, including Infanrix, should be based on careful consideration of the potential benefits and possible risks: For children at higher risk for seizures than the general population, an appropriate antipyretic may be administered at the time of vaccination with a pertussis-containing vaccine, including Infanrix, and for the ensuing 24 hours to reduce the possibility of post-vaccination fever. If any recommended dose of pertussis vaccine cannot be given [see Contraindications (4.2, 4.3), Warnings and Precautions (5.5)], Diphtheria and Tetanus Toxoids Adsorbed (DT) For Pediatric Use should be given according to its prescribing information. Diphtheria The immune system will then be able to produce antibodies more quickly when the person comes into contact with the bacteria or viruses. toxoids (chemically weakened toxins) from diphtheria and tetanus. When Infanrix is administered concomitantly with other injectable vaccines, they should be given with separate syringes. Efficacy of diphtheria toxoid used in Infanrix was determined on the basis of immunogenicity studies. Subjects also received ENGERIX-B and oral poliovirus vaccine (OPV). Pertussis Immune Response to Infanrix Administered as a 3-Dose Primary Series. Procedures should be in place to avoid falling injury and to restore cerebral perfusion following syncope. We comply with the HONcode standard for trustworthy health information -. The vaccination schedule for Infanrix hexa is a course of 2 or 3 doses, given at least 1 month apart, according to official recommendations, usually in the first 6 months of life. These studies showed that booster vaccinations with Infanrix hexa were as effective as giving separate vaccines containing the same active substances 1 month after the booster vaccination. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. Do not administer this product intravenously, intradermally, or subcutaneously. The antigens are purified in successive chromatographic and precipitation steps. General Disorders and Administration Site Conditions. Infanrix hexa has been shown to be effective at producing protective levels of antibodies against diphtheria, tetanus, pertussis, hepatitis B virus, polioviruses, and Hib. The mean length of follow-up was 17 months, beginning 30 days after the third dose of vaccine. Infanrix (Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed) is a noninfectious, sterile vaccine for intramuscular administration. The bovine materials used in these extracts are sourced from countries which the United States Department of Agriculture (USDA) has determined neither have nor present an undue risk for bovine spongiform encephalopathy (BSE). Vaccines administered concurrently with the fourth dose of Infanrix included measles, mumps, and rubella (MMR) vaccine (Merck & Co., Inc.), varicella vaccine (Merck & Co., Inc.), pneumococcal 7-valent conjugate (PCV7) vaccine (Wyeth Pharmaceuticals Inc.), and any U.S.-licensed Hib conjugate vaccine; these were given concomitantly in 13.2%, 6.3%, 37.4%, and 41.2% of subjects, respectively.
Air France - Contact Uk, Salaire Officier Légion étrangère, Profil Aile D'avion, Revenge Saison 4 Acteurs, œuvres Littéraires Au Programme De Seconde 2021, Poser Une Question A Un Cheikh, Mélanie Dedigama Avant, Les étoiles, Académie Lille - Résultats Baccalauréat, Cassin Montebourg, Vaccin H1n1 Composition, Bac Arabe 2020 Algérie, Perle De Culture Teintée, Lyre Achat, W9 En Direct, Angle Of Attack Sensor, Maison à Vendre à 50 Km De Paris, Corrigé Bac Es Maths Amérique Du Nord 2018, Corrigé Bac Français 2014 Pdf, La Belle Et La Bête Cocteau Télécharger Gratuit, Composants Vaccins, Exercices De Maths, Conseillère Rh Salaire, Bac Es 2017 Date, Sujet Bac Français 2006, Cours Anglais Conversation Pdf, Pensée Critique, Info Rashford, Un Quadrant De Navigation, Acheter Synonyme, Problème Enregistrement Ryanair Date De Naissance, Brevet 2020, Guide De Gestion Des Ressources Humaines Pdf, Quand Reprennent Les 4eme Confinement, Numérotation Dents De Lait, Maillot France 2008, étude De Cas Bac Pro Commerce 2018, Etude De Droit Combien D'année, Bac Pro Par Correspondance, Dea Architecture Paris, Reprise Des Cours 3ème Coronavirus, Arsenal Militaire France, Banque Nationale De Sujets E3c Maths, Héra Nom Latin, Alice Pol Amoureuse, Synonyme Honneur 6 Lettres, Maladie D'aujeszky Poule, Eden Bible, Sonia Rolland 2020, Bts Photographie à Distance, Zodiac Occasion, Producteur David Hallyday, Onec Resultat, Bac Anglais 2017 Corrigé Expression écrite, Maths Complémentaires évaluation, Animal Totem Colombe, Lisa Rinna Mari, Nouvelle Star Saison 1 Jury, Mettre La Puce à L'oreille Synonyme, Les Chameaux Du Sahara, Ugo Humbert Maman, Le Dindon Distribution Théâtre, Combien De Moyenne Pour Avoir Le Bac Pro 2020, Olivia - Saison 1 épisode 1, Hors Normes Synonyme, Alain Carré Designer, Symbole + Ou -, Irm Alizes, Carte Catalogne Pdf, Prestige 36, Fiche D'urgence Education Nationale, Drh Définition Fonction, Soticket Le Vip,
Commentaires récents